Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701511 | 1.00 | TDP1 (0.36) | TDP1ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL712328 | 0.81 | ALDH1A1 (0.40) | TDP1ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL13459987 | 0.81 | TDP1 (0.45) | TDP1ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL5358516 | 0.81 | TDP1 (0.45) | TDP1ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL9527402 | 0.78 | TSHR (0.32) | TDP1ALDH1A1LMNA | |
| SCHEMBL784658 | 0.77 | TDP1 (0.45) | TDP1ALDH1A1LMNAHSD17B10USP2 | |
| SCHEMBL9619979 | 0.76 | TET2 (0.34) | TDP1ALDH1A1LMNAUSP2CYP3A4 | |
| SCHEMBL12905144 | 0.75 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL12905143 | 0.75 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNAHSD17B10PRKCA | |
| SCHEMBL1237982 | 0.75 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNAHSD17B10PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014693-A1 | METHOD OF PREPARATION OF PILOCARPINES AND INTERMEDIATES THEREOF | MACFARLAN SMITH LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |