Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229067 | 0.81 | PTGS1 (0.67) | CYP1A2CTBP2KMT2AMEN1USP2 | |
| SCHEMBL29824310 | 0.81 | PTGS1 (0.67) | CYP1A2CTBP2KMT2AMEN1USP2 | |
| Hydrochloric Acid SCHEMBL8693464 | 0.80 | CTBP2 (0.65) | CYP1A2CTBP2KMT2AMEN1USP2 | |
| SCHEMBL8218805 | 0.80 | CTBP2 (0.65) | CYP1A2CTBP2KMT2AMEN1USP2 | |
| SCHEMBL2705455 | 0.80 | PAM (0.67) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL9270423 | 0.78 | CTBP2 (0.58) | CYP1A2CTBP2KMT2AMEN1USP2 | |
| SCHEMBL6788100 | 0.78 | CYP1A2 (1.00) | CYP1A2CTBP2KMT2AMEN1USP2 | |
| SCHEMBL9564049 | 0.77 | CTBP2 (0.55) | CYP1A2CTBP2KMT2AMEN1USP2 | |
| SCHEMBL31249652 | 0.77 | SMN1; SMN2 (0.61) | CYP1A2CTBP2KMT2AMEN1USP2 | |
| SCHEMBL378705 | 0.77 | SMN1; SMN2 (0.61) | CYP1A2CTBP2KMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252474-B1 | HYDRAZINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |