SCHEMBL378705

SCHEMBL378705

COC(=O)Cc1cccc(OC)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.61
CTBP2 P56545 1/20 0.60
CYP1A2 P05177 1/20 0.58
POLB P06746 2/20 0.56
ALDH1A1 P00352 1/20 0.56
HTT P42858 1/20 0.56
MMP13 P45452 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
MTNR1A P48039 2/20 0.55
MTNR1B P49286 2/20 0.55
USP2 O75604 1/20 0.55
SLC7A5 Q01650 1/20 0.55
CHRM2 P08172 1/20 0.53
CHRM1 P11229 1/20 0.53
CHRM3 P20309 1/20 0.53
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31249652 1.00 SMN1; SMN2 (0.61) SMN1; SMN2CTBP2CYP1A2POLBALDH1A1
SCHEMBL4993803 0.89 CTBP2 (0.60) SMN1; SMN2CTBP2CYP1A2POLBALDH1A1
SCHEMBL27424890 0.88 CTBP2 (0.56) SMN1; SMN2CTBP2CYP1A2POLBALDH1A1
SCHEMBL12400239 0.87 SLC7A5 (0.68) SMN1; SMN2ALDH1A1SLC7A5
SCHEMBL4071390 0.85 CTBP2 (0.64) SMN1; SMN2CTBP2CYP1A2POLBALDH1A1
SCHEMBL511950 0.85 POLB (0.56) CTBP2CYP1A2POLBALDH1A1
SCHEMBL4993817 0.85 CTBP2 (0.56) SMN1; SMN2CTBP2CYP1A2POLBALDH1A1
SCHEMBL29640755 0.85 POLB (0.56) CTBP2CYP1A2POLBALDH1A1
SCHEMBL4634509 0.85 SLC7A5 (0.55) SMN1; SMN2CTBP2POLBALDH1A1HTT
SCHEMBL6496853 0.85 POLB (0.59) SMN1; SMN2CTBP2POLBALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096421-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096417-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096424-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096418-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096420-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-107033006-B Preparation method of diaryl ketone 长沙理工大学 2018-12-18 CN claimed
CN-108440299-A A method of preparing 4- nitro benzophenone class compounds 长沙理工大学 2018-08-24 CN claimed
CN-107033006-A Preparation method of diaryl ketone 长沙理工大学 2017-08-11 CN claimed
US-20260138987-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CONTINEUM THERAPEUTICS INC (US) 2026-05-21 US disclosed
EP-4724435-A1 BIFUNCTIONAL AZINES CONJOGATES AS SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF Nurix Therapeutics, Inc. (US) 2026-04-15 EP disclosed
EP-4721737-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES Scinnohub Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP disclosed
US-12565501-B2 Muscarinic acetylcholine M1 receptor antagonists CONTINEUM THERAPEUTICS, INC. (US) 2026-03-03 US disclosed
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) 2025-11-13 US disclosed
US-20250171455-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CONTINEUM THERAPEUTICS INC (US) 2025-05-29 US disclosed
EP-0910563-A4 1999-04-28 EP disclosed
EP-0910563-A1 INTEGRIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1999-04-28 EP disclosed
US-5869658-A POLYMERIC ORGANIC HOST MATERIALS THAT CONTAIN OR THAT ARE COATED WITH THE NOVEL NAPHTHOPYRAN COMPOUNDS, LENSES PPG INDUSTRIES, INC. (US) 1999-02-09 US disclosed
WO-1998030542-A1 VITRONECTIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1998-07-16 WO disclosed
CN-1186806-A Integrin receptor antagonists SMITHKLINE BEECHAM CORP (US) 1998-07-08 CN disclosed
WO-1997001540-A1 INTEGRIN RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1997-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346616-A1 ROCK INHIBITORS AND USES THEREOF ROCK1, ROCK2, RHOA SMN1; SMN2 4305/4885CTBP2 3331/4885CYP1A2 2054/4885
US-12565501-B2 Muscarinic acetylcholine M1 receptor antagonists CHRM1, CHRM2, CHRM3 SMN1; SMN2 2355/4885CTBP2 2061/4885CYP1A2 1141/4885
US-20260138987-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CHRM1, CHRM5, CHRM3 SMN1; SMN2 1733/4885CTBP2 2513/4885CYP1A2 1145/4885
US-20250171455-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CHRM1, CHRM2, CHRM3 SMN1; SMN2 1247/4885CTBP2 2112/4885CYP1A2 865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.