Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | GLS | O94925 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526950 | 0.89 | CTBP2 (0.55) | CTBP2USP2CYP1A2MEN1KMT2A | |
| SCHEMBL21980986 | 0.85 | USP2 (0.59) | CTBP2USP2MEN1KMT2ARAB9A | |
| SCHEMBL9527224 | 0.82 | HTT (0.60) | CTBP2USP2MEN1KMT2ARAB9A | |
| SCHEMBL229067 | 0.78 | PTGS1 (0.67) | CTBP2USP2CYP1A2MEN1KMT2A | |
| SCHEMBL29824310 | 0.78 | PTGS1 (0.67) | CTBP2USP2CYP1A2MEN1KMT2A | |
| SCHEMBL9270423 | 0.78 | CTBP2 (0.58) | CTBP2USP2CYP1A2MEN1KMT2A | |
| SCHEMBL9532375 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1GAAHDAC6 | |
| SCHEMBL4106620 | 0.78 | MEN1 (0.62) | CYP1A2MEN1KMT2ARAB9APOLB | |
| SCHEMBL9527563 | 0.77 | CYP1A2 (0.63) | CTBP2USP2CYP1A2MEN1KMT2A | |
| SCHEMBL378705 | 0.77 | SMN1; SMN2 (0.61) | CTBP2USP2CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | claimed |
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0252474-A2 | Hydrazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |