Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532120 | 0.99 | EPHX2 (0.47) | EPHX2KMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL9527614 | 0.97 | EPHX2 (0.48) | EPHX2KMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL9528579 | 0.92 | ALDH1A1 (0.53) | EPHX2KMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL9528361 | 0.87 | ALDH1A1 (0.50) | EPHX2KMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL9532085 | 0.85 | CYP11B1 (0.45) | EPHX2KMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL10406927 | 0.82 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL9529147 | 0.81 | NOTUM (0.44) | KMT2AALDH1A1MEN1SMN1; SMN2LMNA | |
| SCHEMBL9530556 | 0.80 | MAPT (0.43) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9529321 | 0.80 | ALDH1A1 (0.48) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL9532132 | 0.80 | KMT2A (0.51) | KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |