Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | FABP6 | P51161 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10406927 | 0.86 | ALDH1A1 (0.44) | ATMALDH1A1LMNATBXAS1MEN1 | |
| SCHEMBL9528361 | 0.85 | ALDH1A1 (0.50) | ATMHTTALDH1A1LMNATBXAS1 | |
| SCHEMBL9528579 | 0.85 | ALDH1A1 (0.53) | ATMHTTALDH1A1LMNAMEN1 | |
| SCHEMBL9532147 | 0.84 | CYP1A2 (0.44) | ALDH1A1LMNATP53MEN1MAPT | |
| SCHEMBL9529168 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL9529948 | 0.82 | GAA (0.47) | ATMHTTALDH1A1LMNATBXAS1 | |
| SCHEMBL10407865 | 0.82 | ALDH1A1 (0.44) | FABP6ATMHTTALDH1A1MEN1 | |
| SCHEMBL9532085 | 0.81 | CYP11B1 (0.45) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9528143 | 0.81 | CYP1A2 (0.42) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL9532132 | 0.81 | KMT2A (0.51) | ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |