Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9379655 | 0.87 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9528034 | 0.85 | ADRB2 (0.54) | KDM4EALDH1A1HPGDHSD17B10TOP2B | |
| SCHEMBL9215383 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9734026 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9734023 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9638922 | 0.79 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29576777 | 0.79 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8038539 | 0.79 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29475791 | 0.79 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Ciprofloxacin Ethyl Ester SCHEMBL6779201 | 0.79 | KDM4E (0.74) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562042-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5137892-A | Bactericides | ABBOTT LABORATORIES (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992010191-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-06-25 | — | — | WO | disclosed |