Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530548 | 0.87 | MEN1 (0.48) | IDO1HPGDMAOAMAOBNOS3 | |
| SCHEMBL9530547 | 0.87 | MEN1 (0.48) | IDO1HPGDMAOAMAOBNOS3 | |
| SCHEMBL9528126 | 0.86 | IDO1 (0.57) | IDO1HPGDMAOAMAOBRAB9A | |
| SCHEMBL10453700 | 0.79 | NOS3 (0.49) | HPGDNOS3NOS1SMN1; SMN2MEN1 | |
| SCHEMBL10453699 | 0.79 | NOS3 (0.49) | HPGDNOS3NOS1SMN1; SMN2MEN1 | |
| SCHEMBL10453760 | 0.79 | NOS3 (0.43) | NOS3NOS1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10453761 | 0.79 | NOS3 (0.43) | NOS3NOS1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10453547 | 0.78 | NOS3 (0.47) | MAOAMAOBNOS3NOS1SIGMAR1 | |
| SCHEMBL10453549 | 0.78 | NOS3 (0.47) | MAOAMAOBNOS3NOS1SIGMAR1 | |
| SCHEMBL9529440 | 0.78 | MGLL (0.51) | NOS3NOS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4921939-A | GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS | UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) | 1990-05-01 | — | — | US | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |
| EP-0241395-A2 | Sweeteners derived from n-phenylguanidinoacetic and n-phenylethananamidinacetic acids, and compositions containing such sweeteners | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1987-10-14 | — | — | EP | disclosed |