Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527879 | 0.86 | IDO1 (0.47) | IDO1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9531717 | 0.86 | IDO1 (0.49) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11850430 | 0.81 | HTT (0.44) | SMN1; SMN2ALDH1A1HPGDMAPTLMNA | |
| SCHEMBL21675913 | 0.81 | IDO1 (0.57) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11318419 | 0.76 | IDO1 (0.51) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21132821 | 0.73 | NOS1 (0.45) | SMN1; SMN2ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL2794397 | 0.73 | IDO1 (1.00) | IDO1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8116495 | 0.72 | KMT2A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8116496 | 0.72 | KMT2A (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10776734 | 0.71 | L3MBTL1 (0.45) | IDO1SMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |