Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528078 | 0.93 | CYSLTR2 (0.41) | CYSLTR1CYSLTR2PTGESHTR2A | |
| SCHEMBL9528457 | 0.92 | MEN1 (0.40) | CYSLTR1EPHX2PPARGCYSLTR2MEN1 | |
| SCHEMBL9527270 | 0.91 | MEN1 (0.40) | CYSLTR1EPHX2PPARGCYSLTR2MEN1 | |
| SCHEMBL9531910 | 0.88 | PLA2G4A (0.41) | CYSLTR1EPHX2PPARGCYSLTR2MEN1 | |
| SCHEMBL9526915 | 0.87 | CYSLTR1 (0.40) | CYSLTR1EPHX2PPARGCYSLTR2MEN1 | |
| SCHEMBL9526803 | 0.85 | MEN1 (0.39) | CYSLTR1EPHX2PPARGCYSLTR2MEN1 | |
| SCHEMBL9526859 | 0.84 | B3GAT3 (0.36) | — | |
| SCHEMBL9526614 | 0.84 | PLA2G4A (0.39) | CYSLTR1EPHX2PPARGCYSLTR2MEN1 | |
| SCHEMBL9526764 | 0.84 | NPC1 (0.37) | — | |
| SCHEMBL9528727 | 0.82 | CYSLTR2 (0.42) | CYSLTR1EPHX2PPARGCYSLTR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0337767-A1 | Cyclic amides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |