Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527977 | 0.93 | CYSLTR1 (0.41) | CYSLTR2CYSLTR1HTR2APTGES | |
| SCHEMBL9528727 | 0.89 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1HTR2APTGES | |
| SCHEMBL9528457 | 0.85 | MEN1 (0.40) | CYSLTR2CYSLTR1HTR2APTGES | |
| SCHEMBL9527270 | 0.84 | MEN1 (0.40) | CYSLTR2CYSLTR1HTR2APTGES | |
| SCHEMBL9526859 | 0.84 | B3GAT3 (0.36) | — | |
| SCHEMBL9531910 | 0.83 | PLA2G4A (0.41) | CYSLTR2CYSLTR1HTR2APTGES | |
| SCHEMBL9526764 | 0.83 | NPC1 (0.37) | GAA | |
| SCHEMBL9526915 | 0.81 | CYSLTR1 (0.40) | CYSLTR2CYSLTR1HTR2APTGES | |
| SCHEMBL9489489 | 0.80 | TDP1 (0.43) | MGAMGAASIMGAM2 | |
| SCHEMBL9488371 | 0.79 | GAA (0.43) | CYSLTR2CYSLTR1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |