Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10470254 | 0.98 | HTR2A (0.43) | HTR2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL10763408 | 0.91 | HTR2A (0.43) | HTR2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL9529423 | 0.85 | HTR1A (0.46) | HTR2AHTR1ADRD2 | |
| SCHEMBL9529768 | 0.81 | ALDH1A1 (0.53) | HTR2AMEN1ALDH1A1HTR1AKMT2A | |
| Hydrochloric Acid SCHEMBL9527324 | 0.80 | ALDH1A1 (0.51) | HTR2AMEN1ALDH1A1HTR1AKMT2A | |
| SCHEMBL13532584 | 0.79 | — | — | |
| SCHEMBL9529439 | 0.79 | — | — | |
| SCHEMBL10672091 | 0.78 | HTR2A (0.53) | HTR2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL9602778 | 0.78 | HTR2A (0.53) | HTR2AKDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL9826691 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | claimed |