Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526698 | 0.90 | DRD2 (0.52) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9526324 | 0.85 | — | — | |
| SCHEMBL9529768 | 0.85 | ALDH1A1 (0.53) | HTR1ADRD2HTR2A | |
| SCHEMBL9528044 | 0.85 | HTR2A (0.45) | HTR1ADRD2HTR2A | |
| SCHEMBL9529439 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL9527324 | 0.83 | ALDH1A1 (0.51) | HTR1ADRD2HTR2A | |
| SCHEMBL9526990 | 0.83 | — | — | |
| SCHEMBL10763408 | 0.83 | HTR2A (0.43) | HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL10470254 | 0.83 | HTR2A (0.43) | HTR1ADRD2HTR2A | |
| SCHEMBL10660956 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | claimed |