Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9528146 | 0.98 | OPRM1 (0.38) | OPRM1DRD2SIGMAR1HCAR3HCAR2 | |
| SCHEMBL5696483 | 0.70 | DRD2 (0.36) | OPRM1DRD2SIGMAR1 | |
| SCHEMBL2273415 | 0.69 | OPRM1 (0.64) | OPRM1DRD2SIGMAR1GABRDGABRA1 | |
| SCHEMBL5460348 | 0.69 | DRD2 (0.42) | OPRM1DRD2SIGMAR1HCAR3HCAR2 | |
| SCHEMBL1401191 | 0.67 | OPRM1 (0.50) | OPRM1DRD2SIGMAR1 | |
| SCHEMBL613058 | 0.66 | DRD2 (0.66) | OPRM1DRD2SIGMAR1GABRDGABRA1 | |
| SCHEMBL1266110 | 0.64 | SIGMAR1 (0.46) | OPRM1DRD2SIGMAR1GABRDGABRA1 | |
| SCHEMBL29689237 | 0.64 | SIGMAR1 (0.46) | OPRM1DRD2SIGMAR1GABRDGABRA1 | |
| SCHEMBL20135156 | 0.64 | SIGMAR1 (0.46) | OPRM1DRD2SIGMAR1GABRDGABRA1 | |
| SCHEMBL2270948 | 0.64 | OPRM1 (0.52) | OPRM1DRD2SIGMAR1GABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |