Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741945 | 0.81 | TDP1 (0.62) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL23812449 | 0.80 | ALDH1A1 (0.58) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL1458194 | 0.79 | KMT2A (0.53) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL27536802 | 0.78 | ALDH1A1 (0.56) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL1165669 | 0.78 | TDP1 (0.67) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL3919215 | 0.77 | TDP1 (0.71) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL17652769 | 0.77 | PRKCZ (0.57) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL12856431 | 0.76 | TDP1 (0.68) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL4993714 | 0.76 | TDP1 (0.68) | TDP1LMNASLC6A2SLC6A3KMT2A | |
| SCHEMBL23812473 | 0.76 | TDP1 (0.61) | TDP1LMNASLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |