Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528085 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CYP2D6LTA4HSMN1; SMN2PKM | |
| SCHEMBL19294808 | 0.80 | CYP2C19 (0.64) | ALDH1A1CYP2D6LTA4HSMN1; SMN2PKM | |
| SCHEMBL613704 | 0.77 | LTA4H (0.77) | ALDH1A1CYP2D6LTA4HSMN1; SMN2PKM | |
| SCHEMBL11036914 | 0.77 | LTA4H (0.77) | ALDH1A1CYP2D6LTA4HSMN1; SMN2PKM | |
| Oxalic Acid SCHEMBL9530842 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HTTLMNAGAA | |
| Oxalic Acid SCHEMBL9530845 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HTTLMNAGAA | |
| SCHEMBL18085064 | 0.75 | LTA4H (0.75) | ALDH1A1CYP2D6LTA4HSMN1; SMN2HTT | |
| SCHEMBL9371983 | 0.75 | LTA4H (0.75) | ALDH1A1CYP2D6LTA4HSMN1; SMN2HTT | |
| SCHEMBL2361183 | 0.75 | LTA4H (0.75) | ALDH1A1CYP2D6LTA4HSMN1; SMN2HTT | |
| Oxalic Acid SCHEMBL8813161 | 0.75 | LTA4H (0.65) | ALDH1A1CYP2D6LTA4HSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | disclosed |
| CN-1062349-A | Be used as the croak pyridine class of the 3-replacement of medicine | SMITH KLINE FRENCH LAB (GB) | 1992-07-01 | — | — | CN | disclosed |
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |