Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9530842 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPK1KDM4EHCRTR1HCRTR2 | |
| Oxalic Acid SCHEMBL9527661 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPK1KDM4EHRH3LMNA | |
| Oxalic Acid SCHEMBL9527667 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPK1KDM4EHRH3LMNA | |
| Oxalic Acid SCHEMBL7327867 | 0.80 | SLC6A4 (0.65) | KDM4ECCR3HRH3LMNAGAA | |
| Oxalic Acid SCHEMBL7327873 | 0.80 | SLC6A4 (0.65) | KDM4ECCR3HRH3LMNAGAA | |
| SCHEMBL9528399 | 0.80 | MAOA (0.44) | ALDH1A1KDM4EHRH3LMNASMN1; SMN2 | |
| SCHEMBL9528392 | 0.80 | MAOA (0.44) | ALDH1A1KDM4EHRH3LMNASMN1; SMN2 | |
| SCHEMBL9528085 | 0.76 | ALDH1A1 (0.57) | ALDH1A1LMNAGAASMN1; SMN2MEN1 | |
| SCHEMBL9528092 | 0.76 | ALDH1A1 (0.57) | ALDH1A1LMNAGAASMN1; SMN2MEN1 | |
| Oxalic Acid SCHEMBL9528825 | 0.76 | KDM4E (0.53) | ALDH1A1KDM4EHCRTR1HCRTR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |