Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530209 | 0.88 | MTNR1A (0.44) | MTNR1AMTNR1BGRIN2BMAOAMAOB | |
| SCHEMBL9240988 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL9531034 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1BGRIN2BMAOAMAOB | |
| SCHEMBL9243758 | 0.75 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL9776910 | 0.74 | GRIN2B (0.54) | MTNR1AMTNR1BGRIN2BSIGMAR1SLC6A4 | |
| SCHEMBL9759575 | 0.72 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL9776908 | 0.69 | MTNR1A (0.42) | MTNR1AMTNR1BMAOASIGMAR1SLC6A4 | |
| SCHEMBL9239575 | 0.69 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL8674717 | 0.68 | MTNR1A (0.39) | MTNR1AMTNR1B | |
| SCHEMBL14230253 | 0.67 | GLA (0.41) | MAOBSLC6A4SLC6A2PIN1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270947-B1 | SUBSTITUTED BASIC 2-AMINOTETRALINES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |