Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 5/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529175 | 0.79 | NAMPT (0.45) | NAMPTALDH1A1LMNAIDO1EPHX1 | |
| SCHEMBL10797333 | 0.75 | IDO1 (0.42) | ALDH1A1LMNAL3MBTL1IDO1EPHX1 | |
| SCHEMBL10798861 | 0.75 | IDO1 (0.42) | ALDH1A1LMNAL3MBTL1IDO1EPHX1 | |
| SCHEMBL9528819 | 0.74 | EPHX1 (0.50) | LMNAIDO1EPHX1MEN1MAPT | |
| SCHEMBL10453589 | 0.74 | EPHX1 (0.50) | LMNAIDO1EPHX1MEN1MAPT | |
| SCHEMBL9529344 | 0.74 | EPHX1 (0.50) | LMNAIDO1EPHX1MEN1MAPT | |
| SCHEMBL10453855 | 0.74 | EPHX1 (0.50) | LMNAIDO1EPHX1MEN1MAPT | |
| SCHEMBL9528123 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAL3MBTL1DHODHMEN1 | |
| SCHEMBL10452499 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAL3MBTL1DHODHMEN1 | |
| SCHEMBL9528719 | 0.72 | PKM (0.39) | NAMPTALDH1A1LMNAIDO1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4921939-A | GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS | UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) | 1990-05-01 | — | — | US | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |