Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453589 | 0.86 | EPHX1 (0.50) | EPHX1ABCC9KCNJ11LMNAIDO1 | |
| SCHEMBL10453855 | 0.86 | EPHX1 (0.50) | EPHX1ABCC9KCNJ11LMNAIDO1 | |
| SCHEMBL9529344 | 0.86 | EPHX1 (0.50) | EPHX1ABCC9KCNJ11LMNAIDO1 | |
| SCHEMBL9528819 | 0.86 | EPHX1 (0.50) | EPHX1ABCC9KCNJ11LMNAIDO1 | |
| SCHEMBL9529175 | 0.79 | NAMPT (0.45) | EPHX1ABCC9KCNJ11LMNAALDH1A1 | |
| SCHEMBL10453349 | 0.76 | PKM (0.47) | PKMABCC9KCNJ11LMNAALDH1A1 | |
| SCHEMBL9529415 | 0.74 | EPHX2 (0.44) | EPHX1ABCC9KCNJ11LMNAALDH1A1 | |
| SCHEMBL8915586 | 0.74 | ABCC9 (0.46) | PKMABCC9KCNJ11LMNADHODH | |
| SCHEMBL9529457 | 0.74 | ABCC9 (0.46) | PKMABCC9KCNJ11LMNADHODH | |
| SCHEMBL9530604 | 0.73 | EPHX1 (0.42) | EPHX1ABCC9KCNJ11LMNADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |