Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.46 |
| ▸ | CA2 | P00918 | 14/20 | 0.46 |
| ▸ | CA4 | P22748 | 14/20 | 0.46 |
| ▸ | CA6 | P23280 | 14/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.32 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.32 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527337 | 0.83 | CA1 (0.44) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL10382346 | 0.77 | CA1 (0.39) | CA1CA2CA4CA6 | |
| SCHEMBL9527328 | 0.74 | CA1 (0.50) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL28257537 | 0.71 | NPC1 (0.40) | CA2 | |
| SCHEMBL8946440 | 0.68 | CA1 (0.63) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL27530433 | 0.67 | CA2 (0.46) | CA1CA2 | |
| SCHEMBL9528764 | 0.66 | CA1 (0.53) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL27705952 | 0.65 | HSP90AA1 (0.43) | CA2 | |
| SCHEMBL8946827 | 0.65 | CA1 (0.48) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL28204552 | 0.65 | CA2 (0.50) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |