Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619109 | 0.89 | DRD2 (0.67) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL9528411 | 0.88 | DRD2 (0.53) | MEN1KMT2ANPC1RAB9ADRD2 | |
| SCHEMBL7614912 | 0.83 | DRD2 (0.48) | MEN1KMT2ANPC1RAB9ADRD2 | |
| SCHEMBL7612954 | 0.80 | DRD2 (0.53) | NPC1RAB9ADRD2DRD4DRD3 | |
| SCHEMBL9528492 | 0.78 | MAPT (0.54) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL9529209 | 0.78 | DRD2 (0.71) | DRD2DRD4DRD3SMN1; SMN2DHODH | |
| SCHEMBL18304068 | 0.75 | DRD2 (0.51) | NPC1RAB9ADRD2DRD4DRD3 | |
| SCHEMBL13165012 | 0.74 | DRD2 (0.60) | KMT2ADRD2DRD4DRD3MAPT | |
| SCHEMBL9951462 | 0.74 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4611125 | 0.74 | ALDH1A1 (0.55) | NPC1RAB9ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266326-B1 | NOVEL DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS | Aktiebolaget Hässle (SE) | 1993-03-10 | — | — | EP | disclosed |
| US-5106862-A | DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS | AKTIEBOLAGET HASSLE (SE) | 1992-04-21 | — | — | US | disclosed |
| EP-0266326-A1 | Novel derivatives of benzimidazoles active as anti-ulcer agents | Aktiebolaget Hässle (SE) | 1988-05-04 | — | — | EP | disclosed |