Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ANXA2 | P07355 | 3/20 | 0.45 |
| ▸ | S100A10 | P60903 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528511 | 1.00 | KMT2A (0.45) | KMT2AMAPTANXA2S100A10TSHR | |
| SCHEMBL9529300 | 0.89 | LMNA (0.45) | KMT2AMAPTTSHRSMN1; SMN2LMNA | |
| SCHEMBL9061654 | 0.89 | LMNA (0.45) | KMT2AMAPTTSHRSMN1; SMN2LMNA | |
| SCHEMBL9061660 | 0.89 | LMNA (0.45) | KMT2AMAPTTSHRSMN1; SMN2LMNA | |
| Fumaric Acid SCHEMBL30357983 | 0.83 | LMNA (0.46) | KMT2AMAPTTSHRSMN1; SMN2LMNA | |
| SCHEMBL10552454 | 0.83 | LMNA (0.46) | KMT2AMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10552460 | 0.83 | LMNA (0.46) | KMT2AMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL10554250 | 0.82 | ADRA2A (0.50) | KMT2ATSHRSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL10554254 | 0.82 | ADRA2A (0.50) | KMT2ATSHRSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL10556593 | 0.81 | ALDH1A1 (0.43) | KMT2ATSHRSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269755-B1 | DIBENZ b,e]OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON PHARMACEUTICAL CO (JP) | 1993-11-18 | — | — | EP | disclosed |
| US-4889858-A | ANTIHYPOXIC AGENTS, ANTICONVULSANTS, LIPID PEROXIDATION INHIBITORS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |