Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 2/20 | 0.44 |
| ▸ | ATP4B | P51164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16428100 | 0.81 | STAT3 (0.46) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL5173716 | 0.77 | MAPT (0.53) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL1137675 | 0.76 | HTT (0.47) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL5564213 | 0.75 | BRD4 (0.50) | STAT3HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9270999 | 0.73 | LCK (0.45) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL11114037 | 0.72 | MAPT (0.58) | L3MBTL1MAPTMAPK1TDP1ATP4A | |
| SCHEMBL1093046 | 0.72 | MAPK1 (0.53) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL11176047 | 0.71 | ATP4A (0.60) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL19612191 | 0.70 | MAPT (1.00) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL4239447 | 0.70 | NPC1 (0.49) | MAPTNPC1RAB9AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266326-B1 | NOVEL DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS | Aktiebolaget Hässle (SE) | 1993-03-10 | — | — | EP | disclosed |
| US-5106862-A | DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS | AKTIEBOLAGET HASSLE (SE) | 1992-04-21 | — | — | US | disclosed |
| EP-0266326-A1 | Novel derivatives of benzimidazoles active as anti-ulcer agents | Aktiebolaget Hässle (SE) | 1988-05-04 | — | — | EP | disclosed |