Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19612191 | 0.75 | MAPT (1.00) | MAPTMAPK1TDP1L3MBTL1HTR6 | |
| SCHEMBL9528588 | 0.72 | L3MBTL1 (0.53) | MAPTMAPK1TDP1L3MBTL1ADORA3 | |
| SCHEMBL30257342 | 0.71 | ADORA1 (0.56) | MAPTMAPK1TDP1L3MBTL1ADORA3 | |
| SCHEMBL25079149 | 0.71 | HTR3A (0.48) | MAPTMAPK1TDP1L3MBTL1HTR6 | |
| SCHEMBL2880443 | 0.71 | MAPT (0.81) | MAPTMAPK1TDP1L3MBTL1HTR6 | |
| SCHEMBL9352534 | 0.71 | CTSV (0.51) | MAPTMAPK1TDP1L3MBTL1ADORA3 | |
| SCHEMBL13062563 | 0.71 | MAOB (0.50) | MAPTMAPK1TDP1L3MBTL1ADORA3 | |
| SCHEMBL1093046 | 0.70 | MAPK1 (0.53) | MAPTMAPK1TDP1L3MBTL1HTR6 | |
| SCHEMBL9007487 | 0.69 | MAPT (0.80) | MAPTMAPK1TDP1L3MBTL1HTR6 | |
| SCHEMBL1253794 | 0.69 | MAPT (0.85) | MAPTMAPK1TDP1L3MBTL1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428962-A | Indoles in treatment of peptic ulcers | SCHERING CORPORATION (US) | 1984-01-31 | — | — | US | claimed |
| US-4428962-A | Indoles in treatment of peptic ulcers | SCHERING CORPORATION (US) | 1984-01-31 | — | — | US | disclosed |