Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528635 | 0.83 | EGFR (0.40) | EGFRAURKARPS6KB1CRHR1 | |
| SCHEMBL17085318 | 0.82 | GALR3 (0.54) | EGFR | |
| SCHEMBL9215503 | 0.79 | EGFR (0.47) | EGFRRPS6KB1CRHR1 | |
| SCHEMBL11287675 | 0.79 | EGFR (0.49) | EGFRAURKARPS6KB1CRHR1 | |
| SCHEMBL7992661 | 0.79 | KDM4E (0.41) | EGFRRPS6KB1CRHR1 | |
| SCHEMBL18484598 | 0.78 | CRHR1 (0.53) | EGFRAURKARPS6KB1CRHR1 | |
| SCHEMBL28943348 | 0.77 | AURKA (0.40) | EGFRAURKARPS6KB1CRHR1 | |
| SCHEMBL28943346 | 0.77 | AURKA (0.40) | EGFRAURKARPS6KB1CRHR1 | |
| Oxalic Acid SCHEMBL9523891 | 0.76 | RPS6KB1 (0.45) | EGFRAURKARPS6KB1CRHR1 | |
| SCHEMBL8303141 | 0.75 | EGFR (0.38) | EGFRRPS6KB1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6172321-A | — | — | None | — | — | JP | disclosed |
| JP-H06172321-A | SUBSTITUTED AMINOPYRIMIDINE DERIVATIVE, ITS PRODUCTION AND PEST EXTERMINATING AGENT COMPRISING THE SAME AS ACTIVE INGREDIENT | AGRO KANESHO CO LTD | 1994-06-21 | — | — | JP | disclosed |