Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809603 | 0.84 | CA1 (0.45) | KMT2ACYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL7801314 | 0.83 | ALDH1A1 (0.45) | KMT2ATSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL9204354 | 0.79 | CYP1A2 (0.44) | KMT2ACYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL30951484 | 0.74 | CNR2 (0.42) | KMT2ACYP1A2CYP2C19KDM4EALDH1A1 | |
| SCHEMBL10184712 | 0.74 | KMT2A (0.53) | KMT2ACYP1A2CYP2C19TSHRMAPT | |
| SCHEMBL28965242 | 0.74 | CYP1A2 (0.50) | KMT2ACYP1A2CYP2C19TSHRMAPT | |
| SCHEMBL9201765 | 0.74 | CYP1A2 (0.43) | KMT2ACYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL26117581 | 0.73 | CYP1A2 (0.47) | KMT2ACYP1A2CYP2C19TSHRMAPT | |
| SCHEMBL27937688 | 0.73 | CYP1A2 (0.39) | KMT2ACYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL17895911 | 0.73 | CYP1A2 (0.46) | KMT2ACYP1A2CYP2C19TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355385-B1 | SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5151514-A | Triazine substituted herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-29 | — | — | US | disclosed |
| US-5142060-A | Herbicidal substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| US-5126454-A | PROCESS FOR THE PREPARATION OF SULPHONYLISOUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
| US-5089627-A | Chemical intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5085687-A | HERBICIDAL SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-4988381-A | HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0355385-A1 | Substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones, process and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |