SCHEMBL7809603

SCHEMBL7809603

COC(=O)c1cnn(C)c1S(N)(=O)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.45
CA2 P00918 6/20 0.45
CA9 Q16790 6/20 0.45
CA5A P35218 1/20 0.45
CYP1A2 P05177 3/20 0.42
CYP2C19 P33261 3/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TSHR P16473 1/20 0.39
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
PDE1C Q14123 2/20 0.38
CYP3A4 P08684 1/20 0.38
PKM P14618 1/20 0.38
CA12 O43570 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9528826 0.84 KMT2A (0.40) CA1CA2CA9CA5ACYP1A2
SCHEMBL8477927 0.83 RAB9A (0.47) CA1CA2CA9KMT2AMEN1
SCHEMBL27551847 0.81 CA1 (0.36) CA1CA2CA9CA5AKMT2A
SCHEMBL9660914 0.81 MAPK1 (0.36) CA1CA2CA9CA5ACYP2C9
SCHEMBL8472881 0.81 CA9 (0.42) CA1CA2CA9ALDH1A1KDM4E
SCHEMBL10515781 0.77 CA1 (0.42) CA1CA2CA9CA5ACYP1A2
SCHEMBL3436120 0.76 CYP1A2 (0.51) CYP1A2CYP2C19KMT2AMEN1CYP2C9
SCHEMBL9204354 0.75 CYP1A2 (0.44) CYP1A2CYP2C19KMT2AMEN1CYP2C9
SCHEMBL9661211 0.75 ALOX5 (0.37)
SCHEMBL9661196 0.75 TSHR (0.40) CA1CA2CA9ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727423-B1 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD (KR) 2001-07-25 EP disclosed
EP-0613896-B1 Process for the preparation of sulfonylurea derivatives LUCKY LTD (KR) 1998-07-22 EP disclosed
EP-0727424-A2 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD. (KR) 1996-08-21 EP disclosed
EP-0727423-A2 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD. (KR) 1996-08-21 EP disclosed
US-5534637-A CHEMICAL INTERMEDIATES LUCKY LTD. (KR) 1996-07-09 US disclosed
US-5525730-A Processes for preparation of sulfonylurea derivatives LUCKY LIMITED (KR) 1996-06-11 US disclosed
US-5480993-A Process for preparation of sulfonylurea derivatives and intermediates for the process and process for preparing the same LUCKY LTD. (KR) 1996-01-02 US disclosed
EP-0087780-B2 Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL IND LTD (JP) 1995-02-15 EP disclosed
EP-0613896-A1 Process for the preparation of sulfonylurea derivatives and intermediates for this process LUCKY LTD. (KR) 1994-09-07 EP disclosed
US-4954164-A Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed