Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 16/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | APAF1 | O14727 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24797472 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28756963 | 0.76 | SMN1; SMN2 (0.83) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14434248 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5823003 | 0.74 | ALDH1A1 (0.77) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12059988 | 0.73 | POLB (0.65) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL11845603 | 0.72 | SMN1; SMN2 (1.00) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9529545 | 0.71 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4347357 | 0.69 | SMN1; SMN2 (0.62) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9425942 | 0.69 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL4350019 | 0.69 | SMN1; SMN2 (0.79) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |