Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.54 |
| ▸ | MAPT | P10636 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27692289 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9628596 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9626837 | 0.73 | NPC1 (0.49) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9529540 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9528834 | 0.71 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10453589 | 0.70 | EPHX1 (0.50) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL10453855 | 0.70 | EPHX1 (0.50) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL9528819 | 0.70 | EPHX1 (0.50) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL9529344 | 0.70 | EPHX1 (0.50) | MAPTMEN1KMT2ARAB9AHTT | |
| SCHEMBL9528549 | 0.70 | KMT2A (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| EP-0289430-B1 | SWEETENERS DERIVED FROM GUANIDINOACETIC AND ETHANAMIDINOACETIC ACIDS, THEIR USES AND COMPOSITIONS CONTAINING THESE SWEETENERS | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1992-04-08 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |