Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081036 | 0.81 | AHR (0.43) | MAPTLMNATSHRALDH1A1CYP2A6 | |
| SCHEMBL7566027 | 0.76 | NPC1 (0.39) | TSHRALDH1A1KDM4E | |
| SCHEMBL7702034 | 0.75 | CYP1A2 (0.41) | LMNATSHRHTTALDH1A1CYP2A6 | |
| SCHEMBL3018345 | 0.73 | AHR (0.52) | MAPTTSHRHTTALDH1A1KDM4E | |
| SCHEMBL2186256 | 0.72 | MMP3 (0.47) | MAOAMAOBRHEBMMP3KIF11 | |
| SCHEMBL9529038 | 0.69 | MMP3 (0.43) | MAOAMAOBRHEBMMP3KIF11 | |
| SCHEMBL4446050 | 0.69 | MAOA (0.64) | MAOAMAOBMMP3KIF11MAPT | |
| SCHEMBL4945314 | 0.69 | HSD17B10 (0.46) | MAPTTSHRVCAM1CA12CA2 | |
| SCHEMBL10516966 | 0.69 | ESR2 (0.39) | TSHRHSD17B3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16918828 | 0.69 | MMP3 (0.52) | MAOAMAOBRHEBMMP3KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | claimed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | claimed |