Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.59 |
| ▸ | METAP2 | P50579 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL993762 | 0.78 | NOS1 (0.59) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL29741144 | 0.74 | FGFR1 (0.72) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL29402104 | 0.74 | NOS1 (0.70) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL29364542 | 0.74 | NOS1 (1.00) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL177260 | 0.74 | MAPT (1.00) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL24046742 | 0.74 | NOS1 (0.59) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL29521067 | 0.74 | NOS1 (1.00) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL5902 | 0.74 | NOS1 (1.00) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL1141578 | 0.74 | NOS1 (0.70) | NOS1METAP2MAPTDYRK1AKDM4E | |
| SCHEMBL29559746 | 0.74 | MAPT (1.00) | NOS1METAP2MAPTDYRK1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | claimed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | claimed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | claimed |