Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 1.00 |
| ▸ | METAP2 | P50579 | 3/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 3/20 | 1.00 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.53 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364542 | 1.00 | NOS1 (1.00) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| Hydrazine SCHEMBL16698268 | 0.94 | NOS1 (0.89) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL5562 | 0.83 | NOS1 (1.00) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL21787073 | 0.75 | NOS1 (0.58) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL24046742 | 0.74 | NOS1 (0.59) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL9529035 | 0.74 | NOS1 (0.59) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL277779 | 0.74 | NOS1 (0.59) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL12354 | 0.74 | KDM4E (0.59) | NOS1METAP2DYRK1AMAPTKDM4E | |
| SCHEMBL177260 | 0.74 | MAPT (1.00) | NOS1METAP2DYRK1ACSNK2A1MAPT | |
| SCHEMBL20060303 | 0.74 | KDM4E (0.59) | NOS1METAP2DYRK1AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514780-B | Indazole micromolecular tubulin inhibitor and preparation method and application thereof | 山东第一医科大学附属省立医院(山东省立医院) | 2024-06-28 | — | — | CN | claimed |
| CN-116514780-A | Indazole micromolecular tubulin inhibitor and preparation method and application thereof | 山东第一医科大学附属省立医院(山东省立医院) | 2023-08-01 | — | — | CN | claimed |
| CN-113956234-B | N-phenyl substituted 1H-indazole-3-amine compound, preparation thereof and application of antitumor activity | 温州医科大学 | 2023-07-21 | — | — | CN | claimed |
| WO-2023122498-A1 | ONE-STEP OXIDE BATH FOR IMPROVING ADHESION OF POLYMERIC MATERIALS TO METAL SUBSTRATES | MACDERMID, INCORPORATED (US) | 2023-06-29 | — | — | WO | claimed |
| US-20230199972-A1 | One-Step Oxide Bath for Improving Adhesion of Polymeric Materials to Metal Substrates | MACDERMID, INCORPORATED | 2023-06-22 | — | — | US | claimed |
| CN-115322176-A | 2, 3-dihydrobenzofuranyl substituted 1H-indazole compound and preparation and application thereof | 温州医科大学 | 2022-11-11 | — | — | CN | claimed |
| CN-113956234-A | N-phenyl substituted 1H-indazole-3-amine compound, preparation thereof and application thereof in antitumor activity | 温州医科大学 | 2022-01-21 | — | — | CN | claimed |
| CN-110003187-B | Polyfluoroalkyl substituted benzofuran compound and preparation method thereof | 南京工业大学 | 2021-11-05 | — | — | CN | claimed |
| CN-113307773-A | 6-bromo-3-methoxy-1-phenyl-1H-indazole and synthetic method and application thereof | 上海毕得医药科技股份有限公司 | 2021-08-27 | — | — | CN | claimed |
| CN-110003187-A | Polyfluoroalkyl substituted benzofuran compound and preparation method thereof | 南京工业大学 | 2019-07-12 | — | — | CN | claimed |
| CN-109206455-A | It is used to prepare the aryl ruthenium complex and its preparation method and application for the treatment of liver-cancer medicine | 广西中医药大学 | 2019-01-15 | — | — | CN | claimed |
| CN-109180741-A | Ruthenium (II) complex and its preparation method and application for treating gastric cancer | 广西中医药大学 | 2019-01-11 | — | — | CN | claimed |
| CN-109180737-A | Phototoxicity organic compound and its preparation method and application for treating liver cancer | 广西中医药大学 | 2019-01-11 | — | — | CN | claimed |
| CN-108864204-A | It is used to prepare the aryl ruthenium complex and its preparation method and application of anti-tumor drug | 广西中医药大学 | 2018-11-23 | — | — | CN | claimed |
| CN-108822158-A | Ruthenium (II) complex and its preparation method and application for treating liver cancer | 广西中医药大学 | 2018-11-16 | — | — | CN | claimed |
| CN-108752390-A | With phototoxic antitumoral compounds and its preparation method and application | 广西中医药大学 | 2018-11-06 | — | — | CN | claimed |
| CN-122071464-A | Heterocyclic compound, pharmaceutical composition thereof and application thereof | 上海璎黎药业有限公司 | 2026-05-22 | — | — | CN | disclosed |
| US-12630516-B2 | Compounds | NRG THERAPEUTICS LTD. (GB) | 2026-05-19 | — | — | US | disclosed |
| US-6380242-B1 | FOR DIAGNOSIS AND THERAPY OF CENTRAL NERVOUS SYSTEM CONDITIONS | NPS ALLELIX CORP. (CA) | 2002-04-30 | — | — | US | disclosed |
| WO-2001032660-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR ANTAGONIST ACTIVITY | NPS ALLELIX CORP. (US) | 2001-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630516-B2 | Compounds | CYP4B1, CYP1B1, NR4A1 | NOS1 1237/4885METAP2 4155/4885DYRK1A 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.