Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.33 |
| ▸ | CPA3 | P15088 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530397 | 0.75 | BRS3 (0.40) | CYP1A2PPARGPTGESALOX5MME | |
| SCHEMBL8741267 | 0.73 | PARP1 (0.42) | PARP1PPARGPTGESALOX5CPA1 | |
| SCHEMBL8954337 | 0.72 | EPHX2 (0.38) | CYP1A2PARP1PTGESALOX5 | |
| SCHEMBL7259475 | 0.71 | BRS3 (0.44) | CYP1A2PPARGPTGESALOX5MME | |
| SCHEMBL28161278 | 0.66 | PARP1 (0.41) | PARP1 | |
| SCHEMBL9529092 | 0.65 | PARP1 (0.35) | PARP1 | |
| SCHEMBL9052148 | 0.64 | PARP1 (0.40) | PARP1PPARG | |
| SCHEMBL8954238 | 0.64 | MME (0.51) | MME | |
| SCHEMBL7300579 | 0.63 | FOLH1 (0.70) | CYP1A2PPARGPTGESALOX5CPA1 | |
| SCHEMBL7379087 | 0.63 | BRS3 (0.41) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541705-A4 | SUBSTITUTED 1H-IMIDAZOL-5-YL)ALKANOIC ACIDS | — | 1993-11-10 | — | — | EP | claimed |
| EP-0541705-A1 | SUBSTITUTED 1H-IMIDAZOL-5-YL]ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-19 | — | — | EP | claimed |