Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954337 | 0.77 | EPHX2 (0.38) | PARP1 | |
| SCHEMBL28161278 | 0.75 | PARP1 (0.41) | PARP1 | |
| SCHEMBL9052148 | 0.74 | PARP1 (0.40) | PARP1 | |
| SCHEMBL9512926 | 0.73 | HPGD (0.41) | PARP1 | |
| SCHEMBL8954129 | 0.72 | — | — | |
| SCHEMBL9509544 | 0.71 | APLNR (0.40) | PARP1 | |
| Hydrochloric Acid SCHEMBL9267601 | 0.70 | PARP1 (0.39) | PARP1 | |
| SCHEMBL8741912 | 0.69 | AGTR1 (0.36) | PARP1 | |
| SCHEMBL7115521 | 0.69 | AGTR1 (0.39) | — | |
| SCHEMBL8741267 | 0.68 | PARP1 (0.42) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541705-A4 | SUBSTITUTED 1H-IMIDAZOL-5-YL)ALKANOIC ACIDS | — | 1993-11-10 | — | — | EP | claimed |
| EP-0541705-A1 | SUBSTITUTED 1H-IMIDAZOL-5-YL]ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-19 | — | — | EP | claimed |