Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444890 | 0.81 | POLB (0.47) | LMNAMAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6444893 | 0.81 | POLB (0.47) | LMNAMAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9531037 | 0.73 | L3MBTL1 (0.43) | LMNAMAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9531042 | 0.73 | L3MBTL1 (0.43) | LMNAMAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9531671 | 0.73 | KDM4E (0.43) | LMNAMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL5500889 | 0.73 | LMNA (0.54) | LMNAMAPTSMN1; SMN2POLBTDP1 | |
| SCHEMBL9530274 | 0.72 | NPSR1 (0.42) | MAPTSMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL641903 | 0.71 | POLB (0.62) | LMNASMN1; SMN2POLBTDP1ALDH1A1 | |
| SCHEMBL31237097 | 0.71 | POLB (0.62) | LMNASMN1; SMN2POLBTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1811818 | 0.71 | LMNA (0.52) | LMNAMAPTSMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536424-A1 | NOVEL BENZOPYRAN DERIVATIVE | Japan Tobacco Inc. (JP) | 1993-04-14 | — | — | EP | disclosed |