Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444893 | 0.79 | POLB (0.47) | NPSR1MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL6444890 | 0.79 | POLB (0.47) | NPSR1MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL9529075 | 0.74 | MAPT (0.46) | CES1MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL10780674 | 0.74 | NPC1 (0.47) | NPSR1EPHX2PPARGCES2CES1 | |
| SCHEMBL9529116 | 0.72 | LMNA (0.46) | NPSR1CES2CES1MAPTALDH1A1 | |
| SCHEMBL7213173 | 0.71 | TP53 (0.51) | MAPTNPC1RAB9AGAA | |
| SCHEMBL3731899 | 0.70 | DGAT1 (0.49) | NPSR1EPHX2PPARGCES2CES1 | |
| SCHEMBL668192 | 0.70 | CA12 (0.61) | NPSR1CES2CES1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL3731897 | 0.69 | DGAT1 (0.47) | NPSR1EPHX2PPARGCES2CES1 | |
| SCHEMBL11426640 | 0.69 | CES2 (0.47) | NPSR1EPHX2PPARGCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536424-A1 | NOVEL BENZOPYRAN DERIVATIVE | Japan Tobacco Inc. (JP) | 1993-04-14 | — | — | EP | disclosed |