Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | CASR | P41180 | 4/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9455126 | 0.99 | HTR1A (0.60) | HTR1APOLBESR2CASRADRA1D | |
| SCHEMBL9532833 | 0.83 | CASR (0.59) | HTR1ACASRADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9455227 | 0.82 | CASR (0.58) | HTR1ACASRADRA1DADRA1AADRA1B | |
| SCHEMBL9455114 | 0.76 | CASR (0.50) | HTR1ACASRADRA1DADRA1AADRA1B | |
| SCHEMBL6977935 | 0.76 | CASR (0.50) | HTR1ACASRADRA1DADRA1AADRA1B | |
| SCHEMBL9529252 | 0.76 | CASR (0.50) | HTR1ACASRADRA1DADRA1AADRA1B | |
| Fumaric Acid SCHEMBL9455274 | 0.75 | MAPT (0.45) | HTR1APOLBESR2CASR | |
| SCHEMBL6969866 | 0.75 | HTR1A (1.00) | HTR1ACASR | |
| SCHEMBL10864903 | 0.75 | POLB (0.97) | HTR1APOLBESR2ADRA1DADRA1A | |
| SCHEMBL29353196 | 0.75 | POLB (0.97) | HTR1APOLBESR2ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359790-B1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5084454-A | Tranquilizers and antinausea drugs | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-01-28 | — | — | US | disclosed |