Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9455268 | 0.98 | CASR (0.49) | CASRHTR1AGRM2F10 | |
| SCHEMBL31343494 | 0.84 | GRM2 (0.48) | CASRHTR1AGRM2F10 | |
| SCHEMBL6977935 | 0.84 | CASR (0.50) | CASRHTR1AGRM2ADRA1DADRA1A | |
| SCHEMBL9455114 | 0.84 | CASR (0.50) | CASRHTR1AGRM2ADRA1DADRA1A | |
| SCHEMBL9532833 | 0.80 | CASR (0.59) | CASRHTR1AGRM2ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL9455227 | 0.79 | CASR (0.58) | CASRHTR1AGRM2ADRA1DADRA1A | |
| SCHEMBL3798210 | 0.79 | GRM2 (0.69) | GRM2F10 | |
| SCHEMBL5007547 | 0.79 | GRM2 (0.69) | GRM2F10 | |
| SCHEMBL9700481 | 0.78 | CA2 (0.39) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9696810 | 0.78 | ADRA2A (0.59) | CASRHTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359790-B1 | 1,4-BENZOXAZINE AND 1,4-BENZOTHIAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5084454-A | Tranquilizers and antinausea drugs | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-01-28 | — | — | US | disclosed |