Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.50 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.50 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103990 | 0.76 | ALDH1A1 (0.57) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL8071002 | 0.76 | ALDH1A1 (0.54) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL23384021 | 0.74 | OPRM1 (0.67) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL9223529 | 0.74 | MEN1 (0.55) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL1103890 | 0.74 | OPRM1 (0.61) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL11814185 | 0.73 | MAPT (0.67) | ALDH1A1LMNAMEN1KMT2ACCR1 | |
| SCHEMBL9529108 | 0.73 | APP (0.59) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL240629 | 0.73 | OPRL1 (0.73) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL28299186 | 0.73 | OPRM1 (0.58) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL9678362 | 0.72 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |