Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315425 | 0.85 | OPRD1 (0.54) | APPALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16874836 | 0.82 | OPRM1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL8319710 | 0.82 | SMN1; SMN2 (0.57) | ALDH1A1GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9531918 | 0.82 | L3MBTL1 (0.54) | APPL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6802425 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL5447927 | 0.82 | SMN1; SMN2 (0.45) | APPALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5235210 | 0.81 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7297882 | 0.81 | KMT2A (0.56) | APPL3MBTL1ALDH1A1GAAKMT2A | |
| SCHEMBL9311071 | 0.80 | OPRM1 (0.57) | APPL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1581919 | 0.79 | OPRM1 (0.56) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |