Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525720 | 0.83 | KDM4E (0.52) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9702887 | 0.75 | ALDH1A1 (0.43) | L3MBTL1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL27404855 | 0.70 | ALDH1A1 (0.62) | ALDH1A1HPGDAR | |
| SCHEMBL23462738 | 0.70 | ALDH1A1 (0.48) | L3MBTL1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2469582 | 0.69 | ALDH1A1 (0.64) | ALDH1A1HPGDAR | |
| SCHEMBL2465179 | 0.69 | ALDH1A1 (0.64) | ALDH1A1HPGDAR | |
| SCHEMBL13851936 | 0.69 | ALDH1A1 (0.64) | ALDH1A1HPGDAR | |
| SCHEMBL4604305 | 0.68 | SMPD1 (0.49) | L3MBTL1MAPTTDP1HPGD | |
| SCHEMBL13581220 | 0.68 | ALDH1A1 (0.55) | ALDH1A1HPGDAR | |
| SCHEMBL16596421 | 0.67 | ALDH1A1 (0.57) | ALDH1A1HPGDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |