Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529371 | 0.83 | L3MBTL1 (0.46) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9525541 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1L3MBTL1HPGDGAA | |
| SCHEMBL4696778 | 0.72 | AR (0.50) | KDM4EALDH1A1L3MBTL1MAPTTDP1 | |
| SCHEMBL23462738 | 0.71 | ALDH1A1 (0.48) | KDM4EALDH1A1L3MBTL1MAPTTHRB | |
| SCHEMBL13784760 | 0.70 | AR (0.62) | KDM4EALDH1A1THRBHPGDHTT | |
| SCHEMBL12301282 | 0.69 | CYSLTR2 (0.45) | L3MBTL1MAPTTDP1THRBHPGD | |
| SCHEMBL25852867 | 0.68 | RARB (0.50) | PTPN1TSHR | |
| SCHEMBL7646373 | 0.67 | L3MBTL1 (0.54) | KDM4EALDH1A1L3MBTL1GAAHSD17B10 | |
| SCHEMBL28425205 | 0.67 | ALDH1A1 (0.63) | ALDH1A1HPGDAR | |
| SCHEMBL28419965 | 0.67 | ALDH1A1 (0.54) | ALDH1A1HPGDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |