Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525941 | 0.89 | MAPT (0.31) | CHRM4MAPT | |
| SCHEMBL9446209 | 0.78 | LMNA (0.44) | LMNARAB9ANPC1TP53HPGD | |
| SCHEMBL9526057 | 0.77 | ACACB (0.31) | RAB9ANPC1HPGDSMN1; SMN2ACACB | |
| SCHEMBL9446197 | 0.77 | ALDH1A1 (0.36) | LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9446210 | 0.64 | ALDH1A1 (0.40) | LMNARAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL31458889 | 0.62 | ALOX15 (0.44) | RAB9ANPC1TP53HPGDSMN1; SMN2 | |
| SCHEMBL9446207 | 0.62 | KDM4E (0.36) | LMNAHPGDMAPT | |
| SCHEMBL4952742 | 0.60 | ALDH1A1 (0.37) | LMNARAB9ANPC1TP53HPGD | |
| SCHEMBL30538876 | 0.59 | ALDH1A1 (0.35) | LMNARAB9ANPC1SMN1; SMN2CHRM4 | |
| SCHEMBL2062273 | 0.59 | LMNA (0.53) | LMNARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337263-B1 | ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0337263-A2 | Isoxazol(isothiazols)-5-carboxamides | BASF Aktiengesellschaft (DE) | 1989-10-18 | — | — | EP | disclosed |