Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530684 | 0.80 | LMNA (0.43) | MAPK1TDP1LMNATSHRHPGD | |
| SCHEMBL9528156 | 0.78 | MAPK1 (0.51) | MAPK1TDP1TSHRHPGDCYP3A4 | |
| SCHEMBL282107 | 0.76 | MAPK1 (0.61) | MAPK1TDP1TSHRHPGDCYP3A4 | |
| SCHEMBL1477394 | 0.75 | TSHR (0.54) | MAPK1LMNATSHRHPGDPGK1 | |
| SCHEMBL16774344 | 0.74 | PGK1 (0.53) | MAPK1LMNATSHRHPGDPGK1 | |
| SCHEMBL7081041 | 0.74 | LMNA (0.41) | LMNATSHRHPGDPGK1HTR2C | |
| SCHEMBL1477058 | 0.72 | LMNA (0.44) | LMNATSHRHPGDPGK1HTR2C | |
| SCHEMBL10977285 | 0.72 | LMNA (0.48) | LMNATSHRHPGDPGK1HTR2C | |
| SCHEMBL8878096 | 0.72 | SYK (0.49) | LMNATSHRHPGDPGK1CYP3A4 | |
| SCHEMBL1555247 | 0.72 | MAPK1 (0.56) | MAPK1TDP1TSHRPGK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371240-B1 | USE OF N-PHENYL-SUBSTITUTED OXAZINDIONES AS HERBICIDES AND N-PHENYL-SUBSTITUTED OXAZINDIONES AND SOME PROCESSES FOR THEIR PRODUCTION | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5164498-A | Herbicidal N-phenyl-substituted oxazinediones | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5061310-A | HERBICIDAL N-PHENYL-SUBSTITUTED OXAZINEDIONES AND OXAZINONETHIONES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0371240-A1 | Use of N-phenyl-substituted oxazindiones as herbicides and N-phenyl-substituted oxazindiones and some processes for their production | BAYER AG (DE) | 1990-06-06 | — | — | EP | disclosed |
| EP-0290902-A2 | Condensed (thio)hydantoins | BAYER AG (DE) | 1988-11-17 | — | — | EP | disclosed |