Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530684 | 0.87 | LMNA (0.43) | LMNAPGK1HPGDTSHRNR1I2 | |
| SCHEMBL4593568 | 0.86 | LMNA (0.41) | LMNAPGK1HPGDTSHRNR1I2 | |
| SCHEMBL8887423 | 0.84 | NR1I2 (0.39) | HPGDNR1I2ADRA2AADORA3ADRA2B | |
| SCHEMBL9528816 | 0.83 | CYP3A4 (0.34) | LMNAHPGDTSHR | |
| SCHEMBL9836317 | 0.82 | PPOX (0.40) | LMNAHPGDTSHRHTT | |
| SCHEMBL9620179 | 0.80 | PPOX (0.42) | HPGDHTT | |
| SCHEMBL9533072 | 0.79 | PPOX (0.43) | TSHRADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL10574907 | 0.79 | GLA (0.41) | LMNATSHRHTT | |
| SCHEMBL7003782 | 0.77 | ALDH1A1 (0.47) | LMNAHPGDHTT | |
| SCHEMBL8982274 | 0.77 | LMNA (0.41) | LMNAPGK1HPGDTSHRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7309831-A | — | — | None | — | — | JP | disclosed |
| US-6639070-B1 | 4-substituted 1,3,4-oxadiazines; herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| EP-1187819-B1 | N-SUBSTITUTED PERHYDRO DIAZINE | BASF AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| EP-1187819-A1 | N-SUBSTITUTED PERHYDRO DIAZINE | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001000600-A1 | N-SUBSTITUTED PERHYDRO DIAZINE | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |
| EP-0863142-A1 | Heterocyclic herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5700761-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0745084-A1 | HERBICIDAL TRICYCLIC HETEROCYCLES AND BICYCLIC UREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |
| JP-H07309831-A | PRODUCTION OF ISOTHIOCYANATE DERIVATIVE | SUMITOMO CHEM CO LTD | 1995-11-28 | — | — | JP | disclosed |
| WO-1995022547-A1 | HERBICIDAL TRICYCLIC HETEROCYCLES AND BICYCLIC UREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-08-24 | — | — | WO | disclosed |
| EP-0371240-B1 | USE OF N-PHENYL-SUBSTITUTED OXAZINDIONES AS HERBICIDES AND N-PHENYL-SUBSTITUTED OXAZINDIONES AND SOME PROCESSES FOR THEIR PRODUCTION | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5164498-A | Herbicidal N-phenyl-substituted oxazinediones | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
| EP-0484776-A1 | Arylsubstituted alkyliden-nitrogenheterocycles | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| US-5061310-A | HERBICIDAL N-PHENYL-SUBSTITUTED OXAZINEDIONES AND OXAZINONETHIONES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0371240-A1 | Use of N-phenyl-substituted oxazindiones as herbicides and N-phenyl-substituted oxazindiones and some processes for their production | BAYER AG (DE) | 1990-06-06 | — | — | EP | disclosed |
| US-4859229-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0290902-A2 | Condensed (thio)hydantoins | BAYER AG (DE) | 1988-11-17 | — | — | EP | disclosed |
| EP-0272594-A1 | Bicyclic imides, process for their preparation and their use in crop protection | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-29 | — | — | EP | disclosed |
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |