Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531940 | 0.90 | TBXA2R (0.65) | TBXA2RTBXAS1 | |
| SCHEMBL9528881 | 0.87 | TBXA2R (0.52) | TBXA2RTBXAS1L3MBTL1MRGPRX4 | |
| SCHEMBL9527590 | 0.84 | ALDH1A1 (0.58) | TBXA2RTBXAS1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9529601 | 0.76 | SLC2A1 (0.42) | L3MBTL1ALDH1A1 | |
| SCHEMBL9529177 | 0.76 | ALDH1A1 (0.52) | TBXA2RTBXAS1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL10406688 | 0.76 | ALDH1A1 (0.60) | TBXA2RTBXAS1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9530560 | 0.73 | TBXAS1 (0.58) | TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL9528734 | 0.71 | TBXA2R (0.72) | TBXA2RTBXAS1 | |
| SCHEMBL8805695 | 0.71 | TBXAS1 (0.56) | TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL8805691 | 0.71 | TBXAS1 (0.56) | TBXA2RTBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |