Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529561 | 0.93 | PTPN7 (0.65) | KMT2AMEN1MAPTPTPN7ALDH1A1 | |
| SCHEMBL7651926 | 0.83 | KMT2A (0.67) | KMT2AMEN1MAPTPTPN7ALDH1A1 | |
| SCHEMBL9315471 | 0.80 | MEN1 (0.52) | KMT2AMEN1MAPTPTPN7ALDH1A1 | |
| SCHEMBL7651922 | 0.79 | KMT2A (0.75) | KMT2AMEN1MAPTPTPN7ALDH1A1 | |
| SCHEMBL9530471 | 0.78 | IDO1 (0.53) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL10452499 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL9528123 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL455875 | 0.74 | MEN1 (0.54) | KMT2AMEN1MAPTPTPN7ALDH1A1 | |
| SCHEMBL6814583 | 0.73 | MAPT (0.60) | KMT2AMEN1MAPTPTPN7ALDH1A1 | |
| SCHEMBL9528476 | 0.72 | EPHX1 (0.69) | KMT2AMEN1MAPTPTPN7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |