Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | TACR3 | P29371 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527527 | 1.00 | EPHX2 (0.38) | EPHX2TACR3FAAHMETAP1TLR2 | |
| SCHEMBL9528466 | 0.94 | TACR3 (0.41) | EPHX2TACR3KDM4EMEN1RECQL | |
| SCHEMBL9528223 | 0.87 | TACR3 (0.41) | TACR3FAAH | |
| SCHEMBL9529882 | 0.84 | METAP1 (0.40) | EPHX2METAP1 | |
| SCHEMBL9528534 | 0.83 | TACR3 (0.42) | TACR3FAAH | |
| SCHEMBL9527532 | 0.83 | METAP1 (0.41) | METAP1KDM4EMEN1RECQLKMT2A | |
| SCHEMBL9528353 | 0.81 | TACR3 (0.41) | TACR3MEN1KMT2A | |
| SCHEMBL9527611 | 0.81 | TACR3 (0.41) | TACR3KMT2A | |
| SCHEMBL9527591 | 0.81 | FAAH (0.42) | TACR3FAAH | |
| SCHEMBL9527595 | 0.81 | NCEH1 (0.42) | TACR3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319170-B1 | ACYL DERIVATIVES OF HYDROXY PYRIMIDINES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | claimed |