Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | LSS | P48449 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612547 | 0.87 | MAOB (0.92) | MAOBMAOAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL11647542 | 0.85 | ALDH1A1 (0.68) | MAPTSMN1; SMN2KMT2AALDH1A1LSS | |
| SCHEMBL9529391 | 0.85 | RAB9A (0.72) | MAOBMAOAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL18695068 | 0.84 | ALDH1A1 (0.71) | MAOBMAOAMAPTNPSR1POLB | |
| SCHEMBL11649434 | 0.84 | POLB (0.70) | MAPTSMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL1520659 | 0.84 | MAOB (1.00) | MAOBMAOAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL8612629 | 0.82 | MAOB (0.83) | MAOBMAOAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL6295850 | 0.82 | ALDH1A1 (0.72) | MAOBMAOAMAPTRAB9AMEN1 | |
| SCHEMBL18737741 | 0.82 | MEN1 (0.46) | MAOBMAOAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL18695146 | 0.82 | NAMPT (0.64) | MAOBMAPTSMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907766-B2 | Sweetness receptor antagonist | AJINOMOTO CO., INC. (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9907766-B2 | Sweetness receptor antagonist | AJINOMOTO CO., INC. (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9907766-B2 | Sweetness receptor antagonist | AJINOMOTO CO., INC. (JP) | 2018-03-06 | — | — | US | disclosed |
| EP-3162366-A1 | SWEETNESS RECEPTOR ANTAGONIST | Ajinomoto Co., Inc. (JP) | 2017-05-03 | — | — | EP | disclosed |
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | AJINOMOTO CO., INC. (JP) | 2017-04-13 | — | — | US | disclosed |
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | AJINOMOTO CO., INC. (JP) | 2017-04-13 | — | — | US | disclosed |
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | AJINOMOTO CO., INC. (JP) | 2017-04-13 | — | — | US | disclosed |
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101372-A1 | SWEETNESS RECEPTOR ANTAGONIST | GPR119, GLP1R, SUCNR1 | MAOB 4217/4885MAOA 4407/4885MAPT 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.